Defeating the EN06 Guardian solo in Fallout 76 requires strategic preparation and the right build. Here's how you can approach the battle:

Recommended Build:

Power Armor: Equip a robust set of power armor with the Overeater's mod to reduce incoming damage. The Reflective Legendary Mod (4 Stars) is also beneficial, as it reflects some of the damage back to the EN06 Guardian.

Weapons: Utilize a heavy weapon with the Vampire's mod for sustained health regeneration. Options like a Gatling Gun (which offers easy ammo availability and no wind-up time) or an Auto Axe with Anti-Armor and Electric Mods are effective. Additionally, a Syringer can be used to reduce the boss's resistances for 120 seconds before engagement.

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Perks: Equip perks such as Slugger (increases damage with two-handed melee weapons), Ricochet (reflects incoming projectile damage back to the boss), and Bullet Shield (provides defensive boosts while firing a heavy weapon). Other useful perks include Tenderizer (amplifies damage after hitting the enemy), Bloody Mess (increases overall damage output), Field Surgeon, and First Aid (improves Stimpak efficiency and healing). For electrified weapons like the Auto Axe, Science Perks offer a damage boost.

Mutations: The Marsupial mutation is essential for jumping onto the elevated platform. Other beneficial mutations include Carnivore (enhances melee buffs), Scaly Skin (extra armor), Twisted Muscles (increases melee damage), and Speed Demon (faster reloads and movement).

Battle Strategy:

Approach Carefully: The EN06 Guardian is equipped with an Ultragenetic Shield Generator, rendering it invulnerable to direct attacks unless specific conditions are met. Additionally, the platform features an Electrified Floor Mechanism that can instantly kill anyone standing within close proximity.

Engage from Above: Use the Marsupial mutation to jump onto the elevated platform, positioning yourself above the Guardian. This vantage point allows you to attack while avoiding the electrified floor.

Utilize Heavy Weapons: Employ your heavy weapon to deal substantial damage. The Vampire's mod will help sustain your health during the fight.

Monitor the Shield: Be aware of the Guardian's shield mechanics and adjust your attacks accordingly to exploit any vulnerabilities.

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